In histology, this xylene solvent works for processing and staining tissue samples. Xylene (dimethylbenzene) is a commonly used aromatic solvent with three isomeric forms: ortho, meta-, and para-xylene.Xylenes are one of the highest-volume chemicals produced and used by industry. It can also remove wax from slides for an accurate study of a tissue sample. Clearene is a selected blend of terpenes formulated specifically to replace xylene and toluene in histology and cytology laboratory procedures. Xylene Substitute is a flammable product and must be stored in a flammable fire cabinet. Acetone is a smaller molecule than xylene and it contains an oxygen atom in the molecular structure. Home » Solvents : Formula 83 - 1 gallon The premier xylene substitute for tissue processing and staining in laboratories and research facilities. Xylene, purified- filtered and purified to ensure consistent and reproducible results. A safer substitute for xylene is necessary to minimize its usage. We have experience recycling all xylene substitutes including: Two models of the ProCycler are available depending on the laboratory size. Wide range of quality pathology supplies including xylene & substitutes. Xylene substitute, Neo-Clear®, Sigma-Aldrich®. Xylene is a classified Hazardous Air Pollutant (HAP), Formula 83 is HAP-free. Related Products: Xylene Compare this item Histosol™ - Xylene Substitute Electron Microscopy Sciences NMP is listed under California's Proposition 65 and identified . Xylene Substitute EC Number: 265-068-8 Properties form solution greener alternative product characteristics Designing Safer Chemicals Learn more about the Principles of Green Chemistry. This product is not soluble in water; not for use with water-based paints. Related News: Matthew Cheung, Hong Kong s No. Additional information. It is less oily than other solvent substitutes and therefore dries quickly and does not leave a residue.. Clearene penetrates tissue rapidly without overhardening and is safe to use with all open and closed system tissue processors. Our PathTrue™ laboratory solvent recyclers improve operational and . Polychem's xylene replacement product lasts 7-10 times longer than comparable solvent products. Science. Xylene substitutes and solvent recyclers - a winning combination! Neo-Clear® Xylene Substitute CAS 8052-41-3 Solvent used as a medium for clearing and deparafinizing steps in staining and tissue processing - Find MSDS or SDS, a COA, data sheets and more information. Instructions For Use - Tissue Processing Xylene Substitute has shown best results on closed tissue processors when heat is not used during the normal clearing process. N-methylpyrrolidinone (NMP) is a well-known solvent used in a variety of cleaning, stripping and coatings applications. BTEX—benzene, toluene, xylene-type solvents," said Pasin. Solvents. It is a common component of ink, rubber, and adhesives. 1 It is a colorless . To view your GSA or VA contract pricing . Some of the direct applications for xylene replacements include: Surface preparation & cleaning Post-clean-up You can use it as a cleaner for the tools used with shellac. Contains no xylene or toluene No citrus odor For use in manual and automated systems Polychem® 36 is a xylene substitute that does not create any hazardous waste since it can be used numerous times and is recyclable. Histosol™ is the original high flash point (114ºF TCC) histological clearing agent. High solvency power. Xylene is synthetic hydrocarbon produced from coal tar known for its wide usage as universal solvent . clearing, 6 1.70% of olive oil processed sample showed. Xylene is primarily a synthetic chemical; however, it can occur naturally in petroleum, coal tar, and during forest fires. DANA B. MIRKIN MD, in Haddad and Winchester's Clinical Management of Poisoning and Drug Overdose (Fourth Edition), 2007 XYLENE. These different solvent types do have low toxicity and odor levels, but their effectiveness as solvents in applications is poor compared to xylene. score o f 0, suggesting less rigid than xylene and the. A safer substitute for xylene is necessary to minimize its usage. Spodoptera litura (SL-1) cell and third-instar larvae of S. litura were used as the model system to evaluate the cytotoxicity of essential oils and synergistic effect of cassia oil with rotenone. When the recycled solvent is ready for reuse, the solvent recycler will alert you with an audible alarm and a message on the display. 2505 Parview Road Middleton, WI 53562-2579 800-383-7799 www.newcomersupply.com info@newcomersupply.com SUPPORT/WARRANTY: For assistance regarding this product contact . These petroleum substitutes have a solvent strength . . It can be used as a solvent and clearing agent as well as for dissolving paraffin, waxes, glues, and adhesives. Odorless Mineral Spirits For Pro's and DIY'ers, Klean-Strip is the For Pro's and DIY'ers, Klean-Strip is the leading brand of solvents, thinners, removers, and cleaners that are dependable for reliable results. This can be used as a general-purpose thinner and cleanup solvent. Durable laminate that increases the label strength and resistance. To view your GSA or VA contract pricing . The use of Neo-Clear as a solvent and . Clearing Solvent 100, Xylene Substitute, Electron Microscopy Sciences Supplier: Electron Microscopy Sciences Clearing solvents offer histology and cytology laboratories a safer alternative to xylene. Use this website, Earth911, to search for a registered hazardous waste disposal site. Properties: - Minimal tissue shrinkage. The mounting medium hardens by evaporation of the solvent. But I can't find it at my local Dunn Edwards, HD or Lowe's. . The purpose of this study was to screen essential oils as substitute solvents for rotenone emulsifiable concentrates (EC). Xylene has a sweet smell and is toxic to humans. It is virtually odourless, compatible with most high purity solvents and is characterised by lower evaporation rates than xylene, making it a lower health risk. Warrantied new and refurbished pathology equipment / histology equipment. Its ability to do so stems from its properties and its chemical structure. 1. 12 x 11 x 12 in. - Less toxic than xylene. The ProCycler Plus has a 20 liter (5 gallon) capacity. Dependable 3M adhesive vinyl that is built to resist harsh conditions. turpentine substitutes, turpatine and T.R.P.S., are more similar to turpentine than to mineral spirits. Museum-quality tissue slides can be prepared with Hitosol without change in protocol or . Removes grease, oil and dirt. Denatured alcohol is used for shellac mixing and removing. Cleans brushes and equipment used with oil based paints. A lot of labs can't afford the high cost. Xylene is a colorless mixture of chemically-related hydrocarbons that often finds use as a solvent for paints and printing inks. 2 official, appealed to medical workers to reconsider. There are three forms of xylene: meta-xylene, ortho-xylene and para-xylene. The premier xylene substitute for tissue processing and staining in laboratories and research facilities Please call us at +1-800-941-9484 or e-mail us at supplies@cbgbiotech.com for shipping quote. This product provides all the benefits of toluene without all of the . . link to info/product on Amazon]. It . Xylene is a colorless liquid that had a sweet odor. Let this fully automatic solvent recycler do all the work. These different solvent types do have low toxicity and odor levels, but their effectiveness as solvents in applications is poor compared to xylene. DetailsOur Everclear Xylene Substitute is a safe alternative to xylene. The result of screening assay indicated that essential oil treatments led to . Because it is made from petroleum, Xylene is especially good at cleaning . Unfortunately, these solvents are harmful and therefore adequate substitutes would be useful. - Soluble with alcohol, paraffin embedding media, and mounting media. Xylenes are used as a solvent in printing, rubber, and leather industries. The poorest-performing substitutes for xylene are the paraffinic and isoparaffinic hydrocarbons and the mixtures of paraffinic hydrocarbons with glycol ethers. It may seem odd, but solvents are chemical composites that are similar on a molecular level to the substances they are designed to dissolve. Description. Xylene will also remove certain adhesives, and is an excellent solvent for cleaning tools and equipment immediately after use. Most manufacturers use this synthetic compound as a solvent for paint, lubricants, sealants, and other goods. Use of a 1.7% dishwasher soap aqueous solution at 90°C to dewax before staining and oven drying the stained sections before cover slipping can eliminate xylene from the staining tasks. Permanent, organic mounting medium. A mixture of all three isomers is termed xylol. A xylene substitute for use in histology and cytology. Weight. Toluene, nicknamed "toluol," and xylene, nicknamed "xylol," are the strong, smelly, fast evaporating and "dry" parts of mineral spirits and naphtha. For cleaning and degreasing applications, substitute a water-based material that does not contain toluene. Odorless Mineral Spirits For Pro's and DIY'ers, Klean-Strip is the For Pro's and DIY'ers, Klean-Strip is the leading brand of solvents, thinners, removers, and cleaners that are dependable for reliable results. Neo-Clear™ Xylene Substitute Solvent used as a medium for clearing and deparafinizing steps in staining and tissue processing; CAS Number: 8052-41-3; Synonyms: Mineral Spirits; find Sigma-Aldrich-65351M MSDS, related peer-reviewed papers, technical documents, similar products & more at Sigma-Aldrich Modifications developed by Newcomer Supply Laboratory. Main Menu. Aim: The aim of this study was to evaluate the effectiveness of 1.7% dishwashing solution, 95% lemon water, and 100% coconut oil when compared to xylene as a deparaffinizing agent during hematoxylin and eosin (H&E) staining. By John Brennan. Characteristics of Mercedes Scientific® Xylene Solvent This purified xylene is in liquid form for use during tissue processing and staining. SKU: XS-100. 1 qt. A lot of labs can't afford the high cost. It is ideal for mall labs. Their higher boiling points make it easier to separate from the contaminants. Parts; Kits; Hoses; Seals; xylene solvent substitute Toluene and Xylene. 10 lbs. CAS: 64742-47-8 Clearing solvents offer histology and cytology laboratories a safer alternative to xylene.VWR offers a broad line of reagent droppers, diagnostic kits, and antigens and antisera, for aid in identifying a variety of microscopic organisms. Actually, xylene substitutes are easier to recycle than xylene. Becoming equally well-known, however, are the increasing safety and regulatory concerns related to this material at the state, federal and international level. 3. SAFE-CLEAR Clearant- Xylene substitute, low odor, non-toxic. In this way, it's an important component of ink, rubber, and different types of adhesives. 1-Butanol; sec-Butanol; . Different ones are used depending upon how fast the finish is supposed to dry. . • 5-gallon can • Colorless DANA B. MIRKIN MD, in Haddad and Winchester's Clinical Management of Poisoning and Drug Overdose (Fourth Edition), 2007 XYLENE. Xylene is one of the few chemicals that don't mix with . In solvent blends with low xylene content, direct substitution with one solvent might be possible. More info you will find in Qualicoat specifications page no 15. This selective solvent is safe to use with most plastics and tubing in open and closed tissue processors. Klean-Strip Odorless Mineral Spirits is a premium, highly refined solvent formula that effectively thins and blends well into oil-based paint, stain and varnish. Home; Repair Service; Parts & Seals Menu Toggle. As an alternative to toluene, Polychem® 36 is a safe and highly responsive toluene substitute. When the vapor temperature climbs to the boiling point of xylene, all the alcohol/water contamination will have been collected in the waste container. It is derived from petroleum and, for this reason, has certain advantages over other, similar products. Toluene base. Unfortunately, they are much more expensive than xylene. Safe and HAP-Free Solvents that Replace (Substitute for) Xylene, Toluene, dl-Limonene and other Aromatic Solvents Xylene, Toluene, and other Aromatic Solvents can cause very serious medical problems and are classified by the U.S. Environmental Protection Agency as Hazardous Air Pollutants (HAP) Tested to withstand exposure to Acetone, Dichloromethane, Hydrofluoric Acid, and other tough chemicals and solvents. WHAT YOU NEED TO KNOW ABOUT XYLENE What is Xylene? Hazard safety codes: Xn, Xi, R10, R20, R21, R38. Neo-Mount is a mounting medium consisting of synthetic resins dissolved in the aromatic-free xylene substitute Neo-Clear. This can quickly be ascertained by pouring a bit of xylene over the concrete sealer, letting it work for 20 seconds, removing the excess, and then feeling the sealer. . Xylene (dimethylbenzene) is a commonly used aromatic solvent with three isomeric forms: ortho, meta-, and para-xylene.Xylenes are one of the highest-volume chemicals produced and used by industry. Permanent, organic mounting medium. More Info. Evaluation of biosafe alternatives as xylene substitutes in hematoxylin and eosin staining procedure: A comparative pilot study . A general purpose pure solvent, ideal for thinning most types of oil based paint. Some Cons of Xylene Substitutes: Many xylene substitutes are more costly than xylene itself Some substitutes do not biodegrade easily There exist substitutes that are less contamination-tolerant Some xylene substitutes can't be distilled There are a number of xylene substitutes that take more time to dry completely At this critical moment, I believe the general public would count on medical personnel to fight against the epidemic together, in the spirit of professionalism, he wrote in a blog post on Sunday. 1-Methyl-2-pyrrolidinone; 1-2-Dichloroethane; 1-4-Dioxane; 2-Butanone; Butanols. The primary reason for using a xylene substitute is that they have much lower toxicity than xylene. Diggers Xylene is a specialty solvent based acrylic sealant thinner used for thinning and stripping sealers. Multiple conventional solvent substitutes are available on the market. Solvent Recycling made easy! It can be used in place of xylene for tissue processing, deparaffinization, clearing and cleanup.. Sub-X is a gentle clearant which will not over-harden tissue specimens. Aim: The aim of this study was to evaluate the effectiveness of 1.7% dishwashing solution, 95% lemon water, and 100% coconut oil when compared to xylene as a deparaffinizing agent during hematoxylin and eosin (H&E) staining. density 0.723 g/cm3 application (s) hematology histology greener alternative category Aligned storage temp. Neo-Clear® is an aliphatic hydrocarbon mixture that can substitute the same . Xylene solvent is used in various industries such as printing, rubber manufacturing, and leather processing. Xylene is an aromatic hydrocarbon with the chemical formula C8H10. EMS Xylene Substitute is a flammable liquid and an aspiration hazard. xylol / xylene substitute some paint I bought to paint my iron gate calls for xylol to thin and cleanup. It Is a Powerful Solvent. Employ all routine xylene-substitute clearing agents with the Thermo Scientific™ Shandon™ Xylene Substitute Mountant. The key difference between xylene and acetone is that xylene is a cheap and less toxic solvent, whereas acetone is an expensive and more toxic solvent. Zero VOC Xylene / Toluene Replacement can be used to thin specified oil-based paint, lacquer, varnish, epoxy, adhesives, anti-rust, porch & deck paints and synthetic enamels. It is a colorless, flammable . Unlike xylene Solvent 100 does not produce hard or brittle specimens, even after prolonged exposure. Histosol™ - Xylene Substitute. If your lab manager shares cost information with you (in my experience Xylene Substitute can be recycled with solvent recyclers. But if You don't want to use MEK you should try to use Xylene [affil. It can be used as a solvent and clearing agent, as well as for dissolving paraffin waxes, glues and adhesives. "TBF is slowly getting into that market, but mostly our products are being evaluated for use in the oil and gas industry and that's where we see huge potential for growth." All Substitutes are Not Equal. Zero VOC Xylene / Toluene Replacement can be used to thin specified oil-based paint, lacquer, varnish, epoxy, adhesives, anti-rust, porch & deck paints and synthetic enamels. Unfortunately, they are much more expensive than xylene. As with toluene, formulators are looking for alternatives to meet ever-changing regulatory requirements. It is safer and a more preferable alternative to xylene. These petroleum substitutes have a solvent strength . turpentine substitutes, turpatine and T.R.P.S., are more similar to turpentine than to mineral spirits. In organic chemistry, xylene or xylol (from Greek ξύλον (xylon) 'wood'; IUPAC name: dimethylbenzene) are any of three organic compounds with the formula (CH 3) 2 C 6 H 4.They are derived from the substitution of two hydrogen atoms with methyl groups in a benzene ring; which hydrogens are substituted determines which of three structural isomers results. Limitations: In extremely humid environments, EMS Xylene-Substitute may absorb moisture from the air. Toluene, nicknamed "toluol," and xylene, nicknamed "xylol," are the strong, smelly, fast evaporating and "dry" parts of mineral spirits and naphtha. xylene solvent can even be used as a substitute for toluene. It is ideal for medium and large labs. [ 20] Storage: Store EMS Xylene Substitute at room temperature in a cool place. Various xylene substitutes were tried in the past such as limonene reagents, aliphatic hydrocarbons, vegetable oils and mineral oils to avoid xylene in the laboratory. In standard histological technique, aromatic solvents such as xylene and toluene are used as clearing agents between ethanol dehydration and paraffin embedding. Description. The poorest-performing substitutes for xylene are the paraffinic and isoparaffinic hydrocarbons and the mixtures of paraffinic hydrocarbons with glycol ethers. Sub-X is an economical xylene substitute that is an essentially odorless and nongreasy aliphatic hydrocarbon. Product must be used in compliance with the intended use statement listed on the product or its accompanying product information.Features:- Used as a solvent and clearing agent- Safe alternative to . First of all MEK does not produce cancer (check in Material Safety Data Sheets). May cause eyes, skin and respiratory tract irritation. Refractive index: 1.495 ±0.005 (dry) Viscosity: Medium (120-265 cps at 24°C) This product (s) resides on a Fisher Scientific GSA or VA contract. Subject: [Histonet] Xylene substitute To: ***@lists.utsouthwestern.edu Date: Monday, April 13, 2009, 11:41 AM Does anyone out there in histoland use Formula 83 by CBG Biotech as a . Aim: The aim of this study was to evaluate the effectiveness of 1.7% dishwashing solution, 95% lemon water, and 100% coconut oil. Generally, it's sold as a colorless liquid with a sweet odor. To recycle xylene you should choose a solvent recycler that uses fractional distillation by temperature. - Dries slowly with no residue. They will also strip some finishes . Xylene will also remove certain adhesives, and is an excellent solvent for cleaning tools and equipment immediately after use. The others are various combinations of themselves, as with lacquer thinner. Low boiling alcohol/water will distill over the fractional distillation column first. Mid-to-slow evaporation rate. It's also known as dimethylbenzene or xylol. d-Limonene, purified and Cederwood Oil, purified. Klean-Strip Odorless Mineral Spirits is a premium, highly refined solvent formula that effectively thins and blends well into oil-based paint, stain and varnish. Tissue processors' retorts and conduits can be dewaxed with a 2% solution of a strong glassware laboratory detergent. A safer substitute for xylene is necessary to minimize its usage. 2-8°C Description Application If you are viewing this page as a nonregistered user, the price (s) displayed is List Price. Solvent Recycling is safe! Xylene is widely used as the primary solvent or diluent in formulating solventborne coatings. The first step starts with determining whether the concrete sealant is water-based or solvent-based. can you mix the solvents and recover them by distillation. Vapors can be irritating to mucous membranes, hazardous in case of skin contact, slightly hazardous in case of ingestion. If it is sticky and somewhat damp, it's solvent-based; if not, it's water . CBG's fractional distillation recycling systems enable pathology, histology, cytology, veterinary, dermatological, chemistry and research laboratories to recycle and reuse solvents including xylene, alcohol, acetone, xylene substitutes, formalin and Isopropyl Alcohol (IPA). This histology-grade xylene is ideal for use as a solvent, lubricant and clearing agent. Solvent 100 can be used in all tissue processors and automatic stainers, is benzene-free and has very low odor. remaining 3 8.30% of samples had s ame rigidity as that of. neo-clear(r) xylene substitute manufacturer Dr. Anthony Fauci, director of the U.S. National . High solvency allows for rapid clearing and de-paraffinization. Dimensions. Contact the local hazardous waste disposal site for further instruction. The condensation rate of Neo-Clear is lower than that of xylene, resulting in a slightly longer drying time of 20-30 minutes. A mixture of all three isomers is termed xylol. It's very good at dissolving compounds that dissolve poorly in water, which is why it is so useful. Simply put the used solvent into place, push start and let the solvent recycler do the rest. Buy direct form the manufacturer and save. Xylene is recommended to Solvent Cure Test for Powder Coating by Qualicoat. Stripping solvent based acrylic (SBA) sealers. It has a slower drying time than Toluene, so it is often used to achieve a smooth finish or to have more time to blend oil-based paints together before they dry. However, these substitutes were found to be less effective as clearing agents and more expensive than xylene [ 7 ]. They are used to thin finishes. It is intended to be used as a replacement for xylene where the hazards associated with aromatic hydrocarbon vapors are to be reduced. Ideal for degreasing metals. Features. This makes it very useful in art conservation and restoration works, where it . Toluene base. Manufacturer Name - THERMO SCI ANATOM PATH Manufacturer . Telephone: (800) 543-8496 It can be used as a solvent and clearing agent, as well as for dissolving paraffin, waxes, glues and adhesives. Azer Scientific's Everclear™ Xylene substitute is a safe alternative to xylene. Denatured Alcohols; Esoteric Organic Solvents. Labs can overcome the high cost of xylene substitutes by recycling them. The MiniProCycler has an 8 liter (2 gallon) capacity. The primary reason for using a xylene substitute is that they have much lower toxicity than xylene. Xylene Substitute GHS Chemical Container Label. xylene with score 1 . In thinning paints and varnishes, it can be substituted for toluene where slower drying is desired, and thus is used by conservators of art objects in solubility testing. Rustins Xylene Thinner 500ml Clear is rated 4.7 out of 5 by 63. Xylene is an organic compound having the chemical formula (CH 3) 2 C 6 H 4 while Acetone is an organic compound having the chemical formula (CH 3) 2 CO. Tissues processed with sesame oil and stained using 1.7% DWS were found to be effective alternative to xylene. Summary - Xylene vs Acetone. The visualization of bacteria by means of staining procedures is an important tool for any microbiologist to have at their disposal, and these . Was designed to be a safe substitute to Xylene, claims that Formula 83 is as equally good or better in almost every use as a laboratory solvent. Neo-Clear® is a non hazardous alternative to xylene. Both xylene and acetone can irritate the mucous membranes so people should be careful when using these chemicals. 1 It is a colorless . In addition, these solvents are used for de-waxing paraffin sections. "Evaluation of Xylene Substitutes for Paraffin Tissue Processing." The Journal of Histotechnology 17.2 (1994): 143-149. Toluene and Xylene. Just type "hazardous waste" into the search bar and then enter your zip code. More frequent changes may be necessary. Xylene Replacements. Thinning for solvent based acrylic (SBA) sealers. Xylene is flammable and practically insoluble. Refractive index: 1.495 ±0.005 (dry) Viscosity: Medium (120-265 cps at 24°C) This product (s) resides on a Fisher Scientific GSA or VA contract. If you are viewing this page as a nonregistered user, the price (s) displayed is List Price. 1 qt. The short answer for how to dispose of xylene safely and effectively takes only two steps. Acetone and xylene also both work well as solvents to remove lacquers and paints. Substitute brush, roller, or flow application for spray application.
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